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🍼 Soft stools, sharp minds, happy babies — don’t miss out on the formula that’s got every parent talking!
Enfamil Reguline Baby Formula is expertly crafted to ease infant constipation with a unique blend of probiotics and easy-to-digest proteins, promoting soft, comfortable stools within the first week. Designed for infants up to 12 months, it delivers complete nutrition with 30 essential nutrients including brain-supporting Omega-3 DHA and immune-boosting vitamins. As the #1 pediatrician-recommended formula, it offers peace of mind and convenience in a reusable powder tub, available in a value-packed 4-pack with Subscribe & Save options.








| ASIN | B00ONNVY0K |
| ASIN | B00ONNVY0K |
| Age Range Description | Infant |
| Allergen Information | Milk |
| Best Sellers Rank | #7,024 in Baby ( See Top 100 in Baby ) #73 in Powder Baby Formula |
| Brand Name | Enfamil |
| Customer Reviews | 4.8 4.8 out of 5 stars (3,292) |
| Date First Available | October 19, 2014 |
| Diet Type | Kosher |
| Each Unit Count | 20.4 |
| Flavor | Powder |
| Global Trade Identification Number | 00300875111581 |
| Is Discontinued By Manufacturer | No |
| Item Form | Powder |
| Item Volume | 19.5 Fluid Ounces |
| Item Weight | 78 Ounces |
| Item model number | MJ-180C |
| Manufacturer | Enfamil |
| Manufacturer | Enfamil |
| Manufacturer recommended age | 0 - 1 years |
| Model Number | MJ-180C |
| Number of Items | 4 |
| Part Number | MJ-180C |
| Product Dimensions | 13.06 x 9 x 5.81 inches; 4.88 Pounds |
| Size | 19.5 Ounce (Pack of 4) |
| UPC | 300875111581 |
| Unit Count | 78.0 Ounce |
D**S
Finally Normal Bowel Movements!!
Our little girl was strictly formula fed from day one, and left the hospital using Enfamil Newborn, which worked great...for a while. She never spit up the whole four weeks she was on it, which was great, but we also found that she also didn't have a bowel movement every day or every other day like most newborns, and she also had tons of gas! Talk about a little tooter! She was going every three to four days with normal looking stool, and on her fourth week I started noticing her little tummy slightly distended, and then all chaos broke out with fussiness, extreme gas, and little sleep for both of us. Our pediatrician recommended Enfamil Gentlease, so we went out and started implementing the new formula into her diet. Everything went well for about a week and a half, and I was so happy as she started going a little more regular for the first two days. Apparently that was only her body getting used to the new formula, because after that we noticed her straining with no bowel movement. I, being a new mom, freaked out, and from the doctor's directions gave her dark Karo syrup, but this didn't work either, and we ended up with having to use a suppository. And poor baby was so constipated from the Gentlease that it was a virtual nightmare that I would love to forget, but after struggling to go for an hour and a half with the suppository we finally had success, and a new formula to try from the doctor's orders. This time around we were told to use Enfamil Reguline, and I was very skeptical especially since I kept reading reviews of babies with diarrhea from this formula. But after seeing my little baby struggle like that I was desperate to try anything. Luckily she took this formula with ease, and we happily said bye bye to constipation! We started this formula at night, and the next day gave her Karo syrup, and right after that she had a bowel movement that got the rest of the hard stool out. She did have one explosive diaper later in the day, but I do believe that was a mixture of the Karo syrup and the Reguline working. From then on out she has been going wonderfully every other day with normal stool, no straining whatsoever any more, and I have a much happier baby! She does toot quite a bit on this new formula, but she's otherwise had no issue of gas staying inside of her. Reguline also does seem to be a little thicker than the other two formula's we've tried, and I have noticed it does stain a bit more. Our daughter also spits up, but not horrible amounts either on this one. She was spitting up a lot more on the Gentlease. Otherwise this formula has been great for us, and we will continue to use it! On the downside there are no refill packs (seriously Enfamil? What's up with that?), and I live in a small community and only Wal-Mart carries this formula, and even then they have a tiny supply so when I do buy formula I make sure to buy enough for a few weeks...which equals a lot of $$ being spent. I've also heard people who have WIC cannot use it for this formula, but since I don't have WIC I'm not sure if it still stands. Again, great formula, works like a charm for my daughter, no more constipation with normal baby stools, minimal spit up, and smelly toots, but the cons are no refill packs available or bulk orders available, and Reguline is not readily available in stores. Since this works for my daughter I'm staying on it, but Enfamil needs to see how many people are using this and come out with refill packs. **Update as of 6/15/16** Our daughter is almost seven months now, and still uses this formula. We've introduced food for a few months now, and even with the food she still manages to go almost every day, some days twice! If, and it's a big if, she doesn't go we give her half/half juice mixture with baby water, and that does the trick! We started her on the Parent Choice stage 2 juice of prune/apple, and that works perfectly!! She more than likely will go twice the next day, but we still haven't had any issues at all like we did! She might have a hard stool one day, but the next day it will be soft either by the formula she drinks, or by the juice we give her. Reguline is still the best formula out there for our little one!
E**Z
Cheaper on here than in stores
This formula has been amazing and it’s cheaper to subscribe to this for my baby cause the price is cheaper on here than in store. My baby initially was under weight while trying to breastfeed and she was constipated but in less than a month she chubbed right up and the reguline keeps her extra regular so stay on top of the diaper changes with this formula. The blow outs will happen but she loves her bottles. She is my formula baby and this so far is a great formula.
A**H
Great for constipation
My son was originally drinking similac and had terrible constipation. This formula was recommended by his pediatrician and helped him so much after only about a week of being on it. He’s not struggling anymore in pain. I’m so glad we tried this formula.
F**W
It Works!
I read all reviews prior to purchasing & I was on the fence, yet hopeful. And thank goodness I made the purchase. My LO is 5 weeks old, and was exclusively BF for the first couple of weeks then long story short my supply was not keeping up with the demand. So I began to supplement and was suggested Similac Advanced-Blue Can. (It was ok for a week and then it went down hill. Extreme fussiness, tight tummy, trouble burping and worst of all constipation.) Next, we tried Similac Pro Sensitive (Orange Can) it was an obvious difference immediately after feeding, burping was easier, baby appeared to be happier at first but constipation worsen. She went from 1-2 days of no BM to 2-3 and was sooo uncomfortable. So I did some research and found this Enfamil. I begin giving baby Enfamil at 4 pm on 9/20. She had a little quarter sized poop 24 hours later but was still backed up obviously. But calm and not quite as tense or fussy like with Similac. By 9:30 tonight (roughly 29 hours later she had a large BM. Loose consistency, not quite diarrhea & dark green.) I am grateful this formula worked for our LO. She has had consistent Enfamil every feeding since yesterday. I will update on whether it will become her full time formula or alternative on certain feeds. Update: 7 months later. Still using this formula and will continue to use until she is no longer on formula. I swear by it. Hands down.
S**Y
Really works for kids with constipation
Great for kids with constipation!
J**S
It works
My baby's formula I order often. We've had a few bad deliveries but makes it easier to order it online in a four pack then it is to get it from the store since I'm a stay at home mom
L**Y
Softer poop!
Our baby struggled with hard poop when she was only a few weeks old and would strain, cry, and was generally unhappy on Enfamil gentleease. We had her on Nutramigen for several months and then tried to make the switch back to gentle ease due to the smell and cost of Nutramigen and the fact that she didn’t like the taste. We immediately had the same constipation issues and I tried Reguline as a last ditch effort and within a day my baby had softer poop! I wished that my pediatrician would have recommended it when we were first struggling with her as a newborn! It can be harder to find and doesn’t have the nice refill boxes to save on plastic, but I’ve been so happy that we have a non-stinky formula that our baby likes and tolerates so well.
M**M
Great until delayed??
What on earth happened?? We had the subscription, and it worked so well for 7 months, but all of a sudden our order was supposed to arrive today (Apr 12th) and now it isn't coming until May?? We can't find these big tubs at Walmart anymore... So upset because my little one has used this since the NICU and it's worked wonders for his poops!! Such a great brand, but why is it disappearing??
Trustpilot
2 weeks ago
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