---
product_id: 374771493
title: "Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended"
brand: "cetaphil"
price: "HK$259"
currency: HKD
in_stock: true
reviews_count: 12
category: "Cetaphil"
url: https://www.desertcart.hk/products/374771493-deep-hydration-fragrance-free-48-hour-activation-serum-1-fl
store_origin: HK
region: Hong Kong
---

# Fragrance-free & gentle 48H deep hydration Hyaluronic Acid + Vitamins E & B5 Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended

**Brand:** cetaphil
**Price:** HK$259
**Availability:** ✅ In Stock

## Summary

> 💧 Unlock 48 hours of unstoppable hydration — your skin’s new BFF!

## Quick Answers

- **What is this?** Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended by cetaphil
- **How much does it cost?** HK$259 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.hk](https://www.desertcart.hk/products/374771493-deep-hydration-fragrance-free-48-hour-activation-serum-1-fl)

## Best For

- cetaphil enthusiasts

## Why This Product

- Trusted cetaphil brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Sensitive Skin Savior:** Fragrance-free formula clinically tested to soothe without irritation or clogging pores.
- • **Layerable Lightweight Serum:** Absorbs instantly, perfect alone or as a hydration booster under your favorite moisturizer.
- • **48-Hour Hydration Powerhouse:** Locks in moisture for two full days, keeping your skin plump and radiant.
- • **Vitamin-Infused Skin Nourishment:** Enriched with antioxidant Vitamin E and Vitamin B5 to restore and protect your skin’s natural barrier.
- • **Dermatologist Recommended Confidence:** Trusted by skin experts for effective, gentle care that transforms dry, sensitive skin.

## Overview

Cetaphil Deep Hydration 48 Hour Activation Serum is a dermatologist-recommended, fragrance-free serum designed for sensitive and dry skin. Powered by the exclusive HydroSensitive complex, hyaluronic acid, and vitamins E & B5, it delivers intense hydration that lasts up to 48 hours while soothing and replenishing skin without clogging pores. Lightweight and fast-absorbing, it can be used alone or layered under moisturizers to boost skin’s moisture and improve overall texture and appearance.

## Description

CETAPHIL DEEP HYDRATION 48 HOUR ACTIVATION SERUM instantly absorbs to deeply replenish skin's hydration for 48 hours and improve the overall quality of sensitive skin. Features HydroSensitiv Complex which deepens dynamic hydration and soothes skin sensitivity. This lightweight serum also includes hyaluronic acid, sunflower seed oil, vitamin B5 and antioxidant rich vitamin E to rehydrate and restore skin's appearance while soothing dry skin and dehydrated skin. Can be used alone or layered under face lotion or cream to provide a deep boost to skin's hydration. Designed for sensitive skin, effective yet gentle skin care that won't clog pores or irritate skin; fragrance-free & clinically tested on sensitive skin. DERMATOLOGIST RECOMMENDED for Sensitive Skin.

Review: Super hydrating!!!!!! - When I purchased this item, I'd been dealing with some health issues that left my skin in terrible shape (redness, dull appearance, rough texture, dry, etc). But let me tell you, the first time I used this product, it felt like the heavens opened up, the angels started singing and a light beamed down on me. 🤣 I tested it to see if my face would stay moisturized for 48 hours, and it didn't disappoint. I cleansed my face with a gentle cleanser followed by a hydrating toner. Then I applied this serum. My face didn't feel greasy. A little goes a long way. My face felt so soft and hydrated. And most of all, the redness and dullness had greatly diminished. It has a creamy texture and is fragrance free which I like because I have sensitive skin. But I have to get back to the hydration. My skin feels so plump and smooth and bouncy and shiny. I've been using it for about 6 months and it's definitely a holy grail in my skin care routine. BTW, I'm a 55 year old African American who's currently going through menopause (if that's helpful to anyone). Trust me, if you try this product, you won't be disappointed. And it's very affordable.
Review: Moisturizer/serum - One of the best moisturizer and serums out there on the market just a little pricey though, but if I was rich, I’d buy it again and again and again

## Features

- CETAPHIL DEEP HYDRATION 48 HOUR ACTIVATION SERUM: Exclusive HYDROSENSITIVE complex deepens dynamic hydration and soothes skin sensitivity
- DEEPLY REPLENISHES SKIN'S HYDRATION FOR 48 HOURS: Rehydrates skin to restore the appearance and improve the quality of sensitive skin over time
- INSTANTLY ABSORBS AND IS LAYERABLE: lightweight serum can be used alone or layered under face lotion or cream to provide a deep boost to skin's hydration
- IDEAL FOR DRY AND DEHYDRATED SKIN: Formulated with hyaluronic acid, sunflower seed oil, vitamin B5 and antioxidant rich vitamin E to rehydrate and soothe
- DESIGNED FOR SENSITIVE SKIN: Effective yet gentle skin care that won't clog pores or irritate skin; features a gentle scent & clinically tested on sensitive skin

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B0957ZBGBJ |
| ASIN  | B0957ZBGBJ |
| Active Ingredients | hyaluronic_acid, vitamin_e |
| Best Sellers Rank | #10,980 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #255 in Facial Serums |
| Brand Name | Cetaphil |
| Customer Reviews | 4.6 4.6 out of 5 stars (1,319) |
| Item Form | Serum |
| Item Volume | 30 Milliliters |
| Item Weight | 0.13 Pounds |
| Item model number  | 0299.011700 |
| Manufacturer | Galderma |
| Manufacturer  | Galderma |
| Manufacturer Part Number | 0299.011700 |
| Material Features | Fragrance Free |
| Material Type Free | Fragrance Free |
| Model Number | 0299.011700 |
| Number of Items | 1 |
| Product Benefits | Antioxidant, Hydrating, Moisturizing, Replenishing, Soothing |
| Product Dimensions  | 1.68 x 1.56 x 5 inches; 2.14 ounces |
| Recommended Uses For Product | Hydrating,Provides Vitamins,Sensitivity Relief,Soothing |
| Scent Name | Unscented |
| Skin Type | Combination, Dry, Mature, Normal, Sensitive |
| Special Ingredients | Hyaluronic Acid |
| Target Use Body Part | Face |
| UPC | 302990117004 |
| UPC  | 302990117004 |
| Unit Count | 1 Fluid Ounces |

## Product Details

- **Product Benefits:** Antioxidant, Hydrating, Moisturizing, Replenishing, Soothing
- **Scent:** Unscented
- **Skin Type:** Combination, Dry, Mature, Normal, Sensitive
- **Special Ingredients:** Hyaluronic Acid
- **Use for:** Face

## Images

![Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended - Image 1](https://m.media-amazon.com/images/I/61kXTdxRMzL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: When does the product expire? i just got it yesterday on 06/10/2022. i don't see any exp on the product.**
A: I just received my 3rd purchase of this product....and there is no experience date. I don't care as I use daily and really like it....no worries in my book.

**Q: Is this product antibacterial too?**
A: It does not say anything about being antibacterial. It is mainly for moisturizing the face.

**Q: Do I still have to use a regular moisterizer at night while using this?**
A: I believe you should be ok just with Cetaphil. Excellent product and I don't see a reason to use another one. I can not say don't use it 100% because I don't know how your skin is. Each person's skin is different and has different needs. Sorry if I can not help more.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Super hydrating!!!!!!
*by V***H on April 24, 2024*

When I purchased this item, I'd been dealing with some health issues that left my skin in terrible shape (redness, dull appearance, rough texture, dry, etc). But let me tell you, the first time I used this product, it felt like the heavens opened up, the angels started singing and a light beamed down on me. 🤣 I tested it to see if my face would stay moisturized for 48 hours, and it didn't disappoint. I cleansed my face with a gentle cleanser followed by a hydrating toner. Then I applied this serum. My face didn't feel greasy. A little goes a long way. My face felt so soft and hydrated. And most of all, the redness and dullness had greatly diminished. It has a creamy texture and is fragrance free which I like because I have sensitive skin. But I have to get back to the hydration. My skin feels so plump and smooth and bouncy and shiny. I've been using it for about 6 months and it's definitely a holy grail in my skin care routine. BTW, I'm a 55 year old African American who's currently going through menopause (if that's helpful to anyone). Trust me, if you try this product, you won't be disappointed. And it's very affordable.

### ⭐⭐⭐⭐⭐ Moisturizer/serum
*by M***S on October 2, 2025*

One of the best moisturizer and serums out there on the market just a little pricey though, but if I was rich, I’d buy it again and again and again

### ⭐⭐⭐⭐⭐ Go to skincare
*by C***Y on July 25, 2025*

I love this lotion because it is lightweight and hydrating. There is no fragrance and it really helps with dryness. My husband even used it too. Great value compared to more expensive brands making it my go to skincare.

## Frequently Bought Together

- Cetaphil Deep Hydration Fragrance Free 48 Hour Activation Serum, 1 Fl oz, 48Hr Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & B5, Dermatologist Recommended
- Cetaphil Deep Hydration Healthy Glow Daily Face Cream, 1.7 oz, 48 Hour Dry Skin Face Moisturizer for Sensitive Skin, With Hyaluronic Acid, Vitamin E & Vitamin B5
- CETAPHIL Deep Hydration Refreshing Eye Serum, 0.5 fl oz, 48Hr Hydrating Under Eye Cream to Reduce the Appearance of Dark Circles, With Hyaluronic Acid, Vitamin E & B5 (Packaging May Vary)

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*Product available on Desertcart Hong Kong*
*Store origin: HK*
*Last updated: 2026-03-18*