

✨ Unlock radiant skin with the power of precision micro-boosts!
Medicube Exosome Shot Zero is a cutting-edge Korean liquid skin booster serum featuring 7,500 PPM spicules and 15 million patented Exosome shots. This serum enhances absorption by 242%, combining AHA, BHA, and PHA acids for gentle exfoliation and pore care. Clinically tested and suitable for all skin types, it delivers professional-grade results akin to micro-needling without needles, making it a must-have for millennials seeking glowing, youthful skin.




























| ASIN | B0D137TMRB |
| Best Sellers Rank | #141 in Beauty & Personal Care ( See Top 100 in Beauty & Personal Care ) #6 in Facial Serums |
| Brand | medicube |
| Brand Name | medicube |
| Customer Reviews | 4.5 out of 5 stars 7,137 Reviews |
| Item Form | Ampoule |
| Item Volume | 30 Milliliters |
| Item Weight | 91 Grams |
| Manufacturer | Medicube |
| Number of Items | 1 |
| Product Benefits | Pore Treatment |
| Recommended Uses For Product | Pore Care,Exfoliation,Improving Skin Texture |
| Scent | Aloe |
| Scent Name | Aloe |
| Skin Tone | All |
| Skin Type | Acne Prone, All, Combination, Dry, Sensitive |
| Special Ingredients | alpha_hydroxy, collagen, minerals |
| Target Use Body Part | Face |
| Unit Count | 1.01 Fluid Ounces |
| Use for | Face |
M**E
Best product, prickly but a million times worth it bc it’s not as bad as people say! Buy IT!
Wow! This stuff is legit. I randomly found this on Amazon when looking for skin care products for my 14 year old daughter. I didn’t get this for her. I got it for myself. This product is too inexpensive and good to be true, only it is true! Tbh, I didn’t really research it before I bought it and used it. It was after I used it and how amazing it worked that I started looking more into the product. The 25,000 ppm dose. After just one time of using it, I was in shock as to how soft and smooth textured my skin was. The bottle doesn’t give the best directions about how much to apply so I just started squeezing a little and rubbing it in and a little more and more and more. I probably did about 7 full pumps. It absorbs and dries in just a minute or so. It doesn’t dry sticky or anything. It’s just like a standard nice serum. Now the big thing that all the hype or fear is about is the way it feels. Some say it’s torturous and feels like you are sticking your face in fiber glass or a cactus or something. I beg to differ. Well it does feel a little prickly for sure but it feels more like something that is getting deep in your skin. It feels like it’s working basically. What I noticed now after using this maybe 5 or 6 times over the last 3 weeks is that when you put it on you have 2 options. You can let it sit or you can put your night cream on. I let it sit for about 10 minutes and it does prickle but then I put my heavy night cream on. At first, the night cream makes it feel a little more prickly but then it really starts to just fade away. The longer you leave it sitting without heavy cream the pricklier it gets. I’m pretty tough, so I decided one time to put coconut oil on instead of night cream. Now that enhanced the prickles big time because it’s a carrier oil. But honestly that time was when I got the absolute most and best results from it. I don’t think you have to be afraid of this product at all and it’s prickles. I think you just need to know your limits. If you are sensitive and don’t like the feeling, just try it on your nose or in small areas. Noses are a little more tough because they are exposed to weather more so than other areas of the face, so they aren’t as sensitive. But my nose is actually one of the areas I found that it helped me the most. Cleaned my pores out completely and whether or not it shrunk them, I’m not sure but it sure looks like it to me. The very first thing I thought after seeing results was that something was wrong because this product should be going for probably $150 now $18 or $20. It’s too reasonably priced to not try and I’m almost positive if you can handle a little prickling feeling, you will be stoked on the results. I went and bought like 5 more of them because I was worried that the price would make a huge jump since it was so good. Oh and ready for a little bit of redness that goes away the next day or 2 days and longer pricklies if you use coconut oil but no peeling at all! After the research I realized how innovative and way far beyond the science being used in the USA. Totally worth every penny and feels like you are saving hundreds on micro needling because it has very similar results. I’m so done with micro needling now! Sorry to go off but seriously! I am just in total shock how well this stuff works and how amazing my skin looks. I will post a pic but not right now because I’m in a hurry and shouldn’t even be posting but I couldn’t help it!!
H**S
Timeless beauty in a bottle
I purchased this product and it waz shipped out and delivered on time and with care. I used it right away and I want to give a detailed description about this item I received. I washed my face and I put a good amount on my face and it felt cool on the skin and right away you can feel it working. Rubbing it on the skin feels pretty good and than you start to feel a prickly feeling the more you work it into the skin, it doesn't hurt, it just feels like if you got fiberglass on the skin and you only feel that when touching the skin otherwise you wouldn't feel anything. A lil time went by and my skin started to get a slight sunburn look, it's exactly the same feeling as when you use dermaroller or stamp. It really is a needle less product and does the very same thing. Skin will feel warm cause blood is coming up to the skin which you want, to receive younger looking skin. It's plumping and the pores shrink and skin really looks amazing as it's working. The prickly feeling lasts throughout the night till next day and you wake up with a glow which feels good cause that's what we're looking for being age 53. I also added the medicube jelly collagen cream to give it an extra boost of hydration and adding the collagen it helps getting directly into the skin and the 2 together work wonders! This product helps us to deliver other products deeper into the skin so using the 2 is like a powerful regimen together! You will love the results. I used red light therapy to help as well and the 3 together makes the skin look amazing as well! It seems the more you touch your skin, the more you're allowing the product to work actively. Think of it as dermarolling and adding in serum as well as the red light therapy only the dermaroller has needles. I've used many products throughout time and dermaroller has given me the best results and these products here give exactly the same results only i love the outcome much better! I will continue using these products and highly recommend them to everyone who truly wants to get their glow back and look years younger in such a short time. My only regret is waiting to purchase these products but now I have them and plan on purchasing more. The night time mask is next. I compare this to frownies but much better due to me not ripping the patches from the skin and the mask is less invasive and works exactly the same, you're not missing any part of the skin when be able to apply it all over the face. I can't wait till I can update this after a couple of months of using these products. I had to explain in detail due to comments I've seen about how much it hurt cause it was the reason it took me longer to purchase this. It doesn't hurt and I hope you purchase it and try it cause I know you won't regret it at all. You'll be smiling cause as we age, our bodies change and I know I lost the natural glow i used to have and it's all back thanks to these products!! Thank you medicube for amazing products!! You have a lifetime customer here and with my skin only getting younger, I hope I can be someone that can help others to achieve the look we're all looking for at this age. I have and id love to see others look in the mirror and say wow! I like who I'm looking at😉
K**E
Very Good. Not a "beginner strength" product. Prepare for prickling.
If you're familiar at all with microneedling, this is the same idea. There are little spicy led (to y dissolving needles) in this serum that make micro channels in your skin to allow products to penetrate more deeply. It also has three gentle chemical exfoliants to smooth and brighten skin. It's a fairly thick, non-sticky serum, and it prickles quite a bit when you massage it in. I bought this on a whim and found out later that this is NOT "beginner strength". A starter serum would be a 100 ppm level. 2000 is definitely more intense and I do get some irritation immediately afterward. I own a professional grade microneedling machine, but between setting it up and sterilizing, it just feels like more of a project than I want to do for shallow, frequent needling. This serum is a nice shortcut and really, really speeds up the results I see from other products, and I use it roughly o CD a week.
S**S
WORKSS! But leaves pieces of silver paint all over hands and face... 💔
I love this SO MUCHHHH it makes my skin feel so soft and plump and helps fade my acne scars more than anythingg atm-- especially paired with vitamin c!!! 😊 BUT BRO AFTER USING THIS FOR LIKE 3 months I think??? THE SILVER PAINT STARTED CHIPPING OFF AND GETS ALLL over my hands before I get to even use it... Like look at it vro...💔 Then I'm rubbing pieces of silver all over my face, into my skin etc. and it sticks like glitter... It's the WORST bro it's soso so annoying plz this part of it is so unnecessary plzz js make it white without the silver coating 💔 Love u... Anyway the product itself works really nicely!! I use it every night (mostly) followed by a moisturiser and definitely works out. 😊 Did exactly what advertised for chat 🗣 Feels and looks more plump, softer, less texture and lightens scarring!!! #awesome It stings a lil but it feels nice idk feels fancy and didn't cause any trouble with my skin barrier, just stung like exfoliation but less ykyk?! I have dry/combination skin and not prone to acne and 17f🙏 Def worth the moneyy u should snag it if u want to scrub off all the silver 🥰 JOKE but unironically it's goated ok bye
J**.
Great product, worth trying even if you like products you already use.
Great stuff! Leaves skin feeling and looking moist and plump. Not sticky, fast absorbing. Feels tingly when applying, but not painful. Skin has shown consistent results after using it every other day for a couple weeks.
J**N
Amazing PDRN
Im obsessed with this PDRN. it gives a light sting and I love that. It brings out a natural glow. I apply at night, obviously.. so it compliments my skin routine and helps plump and hydrate. It has been a great addition. And I love medicube..I dont notice a scent, so thats a bonus to me. Its not sticky, it absorbs rather quickly.. a small drop is all thats needed for each face section and neck. Great product and great price
A**E
Yes this product does work very well with an already established skincare routine.
Ima be honest, I was skeptical on how well this product works after hearing it all over tiki tok but they are definitely onto something. I got the exosome 2000 yesterday and used it the same night. I admit, yes it does itch and sting but its tolerable and went away after like 30 - 45 mins of using. It didnt make my skin red, which was surprising. My current routine is: Pm only; - anua oil cleanser - anua deep pore cleanser - anua 70 toner - (now) medicue one day exosome shot 2000 - (now) corsx vitamin c 23 - corsx snail mucin essence - Neutrogena firm moisturizer or anua daily lotion [ i like to switch between the two ] Im 31 years old, my skin is textured with dark spots, dull and I have a chubby face with few fine lines, scars and huge pores on the apples of my cheeks and some on my nose. I get millia under my eyes/ on the top of my cheek sometimes. Its not too close to the thin skin under my eyes. Today ( the next morning) I noticed my pore are visibly smaller. Wow really?! Yes really! even after 1 use. It's like an exfoliant that my skin needed. (Paula's choice bha, aha exfoliating toner sucks and did not work for me). I noticed my skin was softer and the Milia looks like it opened up and the ball inside is ready to fall out. This product will become part of my skincare routine for sure! I will repurchase and highly suggest this product.
P**E
Great stuff
First, I want to share that I’m fairly knowledgeable about skincare actives and have built solid routines in the past. A few years ago, due to significant health issues, I stopped prioritizing skincare altogether. Now at 55, I’ve decided it’s time to care for my skin again. I purchased Medicube One Day Exosome Shot 2000 on a whim after reading great reviews, mainly to address dullness and enlarged pores. What initially caught my attention was the delivery system—it seemed thoughtfully designed and potentially very effective for resurfacing and product absorption. Although my skin has historically tolerated acids well, it had been quite some time since I used anything resurfacing, so I started with the 2000 PPM formula. I applied it using both rubbing and patting techniques, and experienced no burning or tingling, which was reassuring. After purchasing, I took a more analytical approach to rebuilding my routine and evaluated all of my current products together for long-term skin health (using AI). This product made the “keep” list. The recommendation was to use it strategically—about once per month—as a targeted treatment to stimulate cell turnover and enhance absorption of select follow-up products. I even considered returning it, but after reviewing how it fit into a multi-year skincare plan, it still stood out as beneficial. Rather than being an everyday product, it works best as a periodic reset for dull or congested skin. So far, I’m impressed with how thoughtfully this fits into a structured routine, and I appreciate that it delivers resurfacing benefits without irritation. For anyone rebuilding their skincare regimen or looking for a targeted monthly treatment to improve texture and radiance, this is definitely worth considering.
Trustpilot
2 weeks ago
2 months ago