Question 1

A.c.grace co says that 'vitamin e' interferes with the absorbtion of 'tocotrienols'. why do you use both in yours?

Accepted Answer

No, alpha-tocopherol does not significantly interfere with tocotrienol absorption. It is perfectly fine to take alpha-tocopherol with tocotrienols.We have seen recommendations online to avoid alpha-tocopherol when taking tocotrienols because it may “counteract” the benefits of tocotrienols. However, this is misleading for several reasons.Nearly all of the human research that’s been conducted on tocotrienols has used palm-based tocols, which is comprised of about 25% alpha-tocopherol. At least 12 human clinical trials with palm-based tocols show that tocotrienols reach the bloodstream and vital organs after oral intake despite the co-occurrence of alpha-tocopherol. (1)Furthermore, studies examining high doses of mixed tocols, tocotrienols, and/or alpha-tocopherol (>500 mg/day) have found that the blood level of tocols increase proportionately to the dose taken. (2, 3, 4) Thus, the ratio of tocols supplemented will match the ratio in the blood stream, and the dose of tocols that can absorb at any one times appears to be limitless. In other words, there is no competition or discrimination between the various forms of vitamin E during digestion and absorption.However, research does suggest that prolonged supplementation with high doses of isolated alpha-tocopherol (>150 mg/day) accelerates excretion of all forms of vitamin E, which causes tocotrienol concentrations to decline within the body. (5) For this reason, it is recommended to avoid supplementation with excessive amounts of isolated alpha-tocopherol, regardless of tocotrienol supplementation.1) Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients.Patel V, et al.J Nutr. 2012 Mar;142(3):513-9.2) Evaluation of Pharmacokinetics, and Bioavailability of Higher Doses of Tocotrienols in Healthy Fed HumansQureshi AA, et al.J. Clin. Exp. Cardiolog., 20163) Discrimination between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolismTraber MG, et al.J. Lipid Res., 19924) Plasma tocopherol concentrations in response to supplemental vitamin EDimitrov NV, et al.Am. J. Clin. Nutr., 19915) Supplementation of diets with alpha-tocopherol reduces serum concentrations of gamma- and delta-tocopherol in humansHuang HY, et al.J. Nutr., 2003

Question 2

How many IU's is this?

Accepted Answer

Hello, as stated before, the bottle says 17 IU of d-alpha-tocopherol (57% of Daily Value), along with 50 mg of tocotrienols (alpha, beta, gamma and delta forms of both tocotrienols and tocopherols). From what I've seen, converting from mg to IU for the various Vitamin E isomers looks to be a bit complicated, so I'd ask you to research that. Take care, -John

Question 3

My bottle says it has it has sorbitol + 20 IU d-alpha tocopherol, why the change of ingredients from the listing?

Accepted Answer

I get your point, you are not really wanting an answer, you are making a rhetorical statement!  Thank you for this question... Very helpful.  I personally think if you are not getting what was advertised or promised, you should file a return and leave a review describing your experience. 
 Clearly Sorbitol sounds like an unusual ingredient to have in a vitamin E supplement.  Regarding the other person who told you to discuss elsewhere is a shill and undermines the public visibility of information about products.  If you do find useful information about this product, feel free to post a review on amazon so everyone can benefit.  Thank you again!

Question 4

Anyone notice any new hair growing on their head after starting with this supplement? If so, how long did it take to start seeing results?

Accepted Answer

My usage of this product is to complement the usage of tocopherols (alpha, beta, gamma, delta), all eight of which makes up what is called Vt E which has other antioxidant, anti aging, anti cardio vascular disease, and so on properties. I have not seen any change in hair growth from the use of this product either from this company or another and I have been taking this for well over a year.

Product Dimensions	5.41 x 5.41 x 9.53 cm; 49.9 g
Target Age Range Description	Adult
Target Gender	Unisex

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Doctor's Best Natural Vitamin E, Tocotrienol, Tocomin Supra Bio, 1.8 oz (50 mg), 60 Tablets

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