Can I mix this with API Quick Start and API Stress Coat+ in a gallon every time I do water changes weekly? Or just pour it directly in my 5.5 tank?

In short, you don't need the Stress Zyme if you already are using the Quick Start. Here's a longer answer:The API Stress Coat is primarily a de-chlorinator and has aloe added to help maintain a healthy slime coat on the fish so this should always be added to the water and mixed before adding to the tank. The API Quick Start is meant to jump start the biological cycling of a tank and is only needed for new tanks or potentially semi established tanks that have a spike in ammonia and nitrite levels which could be caused by adding more fish. You can stop using this once your water chemistry has stabilized. API Stress Zyme is very similar in function to the Quick Start and is generally chosen to improve water clarity or stabilize chemistry in more established tanks. You don't need to use both simultaneously and would probably never see the difference compared to using just one. On another note, I always add my bacteria after there is no chance there is any chlorine so they have a better chance of proliferating. I would add either the Quick Start or the Stress Zyme the day after a water change, directly into the tank.

can i mix stress coat, stress zyme and tap water conditioner? if so what amount of each should i mix? doing this harm my fishes?

Stress Coat and water conditioner is the same. ( stress Coat is water conditioner ). if you use both at the same time that you double it up. Maybe it is nothing will happening . But, it is not necessary to do that.

How long this product can be stored before it expires? Also, would its effectiveness reduce during long time storage?

As for length of time you can store, I use it weekly and it lasts for about four months or so. Does not seem to lose effectiveness in that time.

What is the expiration date on this Stress Zyme? It seems very inexpensive.

There is an expiration date on the bottle, however, these are live bacteria and once the bottle is open the shelf life is cut in half. Same as Seachems Pristine. Buy the size bottle for your tank. There is 250ml and 500 or 750ml, depending on the brand. My personal and professional advice is buy the smaller one 1st and see how much you go through, follow the instructions completely. They work well, keeps the glass cleaner longer. Also very important, make sure the aeriation is adequate and they say to change the filters 1st. If you have the $$ go for it. Best and least expensive and just as sufficient, is to change them half way before you normally change out your filters. API Stress zyme seems to keep its life span quite a while after opening. But trust me, you'll use it up way before it expires. Compared to the other similar products, this one seems to leave more of a brownish pile on the corners or underneath Ornaments, whis in turn will have to be vacuumed, netted or a baster for cooking depending on the size of your tank. 👍

Item model number	56E
Is Discontinued By Manufacturer	Yes
Item Form	Liquid
Volume	16
batteries required	No
Batteries Included	No

Stress Zyme 16oz

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